Understanding Triple-Negative Breast Cancer: Causes and Treatment Options

Triple-negative breast cancer (TNBC) affects about 10-15% of those diagnosed with breast cancer. Early detection and breast cancer treatment are crucial for improving outcomes, as this type lacks the common receptors that fuel most breast cancers.

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Voyagerix/Shutterstock
Voyagerix/Shutterstock

What is Triple-Negative Breast Cancer?

TNBC is characterized by cancer cells missing estrogen, and progesterone receptors, and high HER2 levels. Without these markers, TNBC can be more challenging to treat, requiring a unique approach.

Causes and Risk Factors

Key factors influencing TNBC include genetic mutations, particularly in the BRCA1 gene, late pregnancies, sedentary lifestyles, and vitamin D deficiency. Premenopausal women and those under 50 are often at increased risk.

Symptoms to Watch For

TNBC symptoms align with other breast cancers, like breast lumps, swelling, changes in shape, and nipple discharge. Detecting these early can significantly affect treatment success.

Stages and Prognosis

TNBC progresses across five stages, from abnormal cell development to spreading beyond the breast. Stage 0 involves early abnormal cells, while Stage 4 indicates spread to other organs.

Treatment Options

Treatment may involve surgery (lumpectomy or mastectomy), radiation, and chemotherapy, especially in advanced stages. These methods target malignant cells and aim to prevent recurrence.

Side Effects to Consider

Side effects such as nausea, fatigue, skin changes, and lymphedema may accompany treatment, requiring additional care and interventions.

With advancements in treatment, the five-year survival rate for localized TNBC is now 91%. Alongside medical care, adopting a healthy diet rich in phytochemicals while avoiding certain processed foods can support recovery processes. Consult a healthcare provider to understand personalized treatment and lifestyle adjustments for managing TNBC effectively.